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Losartan blocks EndMT in mitral valve endothelium
Learn more about our current research
Perfused human blood vessels (red) formed with ECFC connect with mouse (green)
Learn more about our current research
Blood Vessels in Hemangioma
Learn more about our current research
A “CRISPR” view of Sturge-Weber syndrome is coming into focus
Read the 2017 story about one of our projects
An MRI image reveals capillary malformations caused by Sturge-Weber syndrome.
Read more about our work on Sturge-Weber syndrome
SOX18 in infantile hemangioma
Graphical Abstract
Huang et al 2021 ATVB
Angiopoietin-2 in Capillary Malformations
Graphical Abstract

Welcome

Our lab studies the role of endothelial cells and pericytes in vasculogenic and/or angiogenic diseases.  We have three main areas: (1) vascular tumors (infantile hemangioma), (2) vascular malformations (e.g., capillary malformation), and (3) endothelial to mesenchymal transition (EndMT) in mitral valve endothelium after myocardial infarction and potential for EndMT to contribute to fibrosis and stiffening of mitral valve leaflets.