Lab Members


Joyce Bischoff, PhD

Principle Investigator

Joyce Bischoff received an A.B. in chemistry from Duke University and a Ph.D. in biochemistry from the Washington University School of Medicine. She was a post-doctoral fellow at the Whitehead Institute for Biomedical Research. She joined the Surgical Research Laboratories, now called the Vascular Biology Program, at Children's Hospital in 1990. She was promoted to Professor, Department of Surgery in 2010.  Contact


Luke Borgelt, BA

Research Assistant

Luke Borgelt graduated from College of Wooster in May 2021 with a BA in Biochemistry and Molecular Biology.

His senior thesis entitled "Reconstitution of Hydroxylation Activtiy by the NDH and 6-HDH Enzyme Complexes from Bacillus niacini with the Addition of a Novel CoxG Enzyme" was carried out in Dr. Mark Snider's lab. 

He is working on molecular characterization of stem cells and endothelial cells in infantile hemangioma.


Annegret Holm, MD 

Research Fellow 

Dr. Holm graduated from Medical School at the University of Heidelberg.  She conducted her MD Thesis studies, entitled "Characterization of transgenic mouse models for the study of microvascular
mural cells," in the laboratory of Dr. Hellmut Augustin.  Her residency training is in the Department of Pediatric Hematology/Oncology at University Hospital Freiburg.

Dr. Holm is working on the mechanims by which the R+ enantiomer of propranolol inhibits hemangiomaa formation.


Lan Huang, PhD

Instructor in Surgery

Dr. Huang completed her PhD degree in Biochemistry and Molecular Biology from Indiana University School of Medicine in 2009. She joined Dr. Bischoff's Laboratory as a postdoctoral fellow in 2010. In 2015 she was promoted to Instructor in Surgery. Dr. Huang focuses on endothelial cell biology in health and in diseases, with an emphasis on endothelial cells in vascular anomalies. Over last 4 years, Dr. Huang has studied venous malformation (VM), capillary malformation (CM) and Sturge-Weber Syndrome (SWS).  Her investigations will ultimately enable us to identify therapeutic targets and develop treatments for patients with these vascular disorders. Contact  


Jay Lemon

Undergraduate Researcher


Jay is a senior at Harvard College studying Molecular and Cellular Biology. He joined Dr. Bischoff's Lab in July 2020 and works on the SWS project, investigating endothelial cell barrier integrity in CM.




Sana Nasim, PhD

Postdoctoral Research Fellow


Sana Nasim received her B.S in Biomedical Engineering and a minor in Applied Mathematics from New Jersey Institute of Technology and a Ph.D. in Biomedical Engineering from Florida International University in 2020. Right after she joined Bischoff’s laboratory as a postdoctoral fellow where she focuses on capillary malformations caused by the GNAQ R183Q mutation in endothelial cells and interaction of the mutant endothelial cells with the surrounding mural cells.



Jill Wylie-Sears, MA

Research Technologist I

Jill obtained her Master of Science in Plant Molecular Biology from University of Michigan and her Master of Arts in Professional Writing with a concentration in Biomedical Sciences from Western Michigan University in 1998.  In 2001, Jill joined the Bischoff Lab as a Research Technician with graduation to Research Technologist I. Contact