Research

Overview

Our lab studies the role of endothelial cells and pericytes in vasculogenic and/or angiogenic diseases.  We have three main areas: (1) vascular tumors (infantile hemangioma) and (2)vascular malformations (e.g., capillary malformation), (3) endothelial to mesenchymal transition (EndMT) in mitral valve endothelium after myocardial infarction and potential for EndMT to contribute to fibrosis and stiffening of mitral valve leaflets.  Please see the links on the left for detailed descriptions of our projects.

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Funding

Our work is currently supported the National Heart Lung and Blood Institute (NHLBI), Boston Children's Translational Neuroscience Center, the Sturge Weber Foundation, and the National Institute for Child Health and Human Development.  


SWF
NHLBI