Losartan blocks EndMT in mitral valve endothelium
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Perfused human blood vessels (red) formed with ECFC connect with mouse (green)
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Blood Vessels in Hemangioma
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A “CRISPR” view of Sturge-Weber syndrome is coming into focus
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An MRI image reveals capillary malformations caused by Sturge-Weber syndrome.
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SOX18 in infantile hemangioma
Graphical Abstract
Huang et al 2021 ATVB
Angiopoietin-2 in Capillary Malformations
Graphical Abstract


Our lab studies the role of endothelial cells and pericytes in vasculogenic and/or angiogenic diseases.  We have three main areas: (1) vascular tumors (infantile hemangioma), (2) vascular malformations (e.g., capillary malformation), and (3) endothelial to mesenchymal transition (EndMT) in mitral valve endothelium after myocardial infarction and potential for EndMT to contribute to fibrosis and stiffening of mitral valve leaflets.